PXD070528

PXD070528 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Characterization of the Angiosarcoma Microenvironment
Description	Angiosarcomas are ultra-rare, highly aggressive sarcomas with limited treatment options and dismal prognosis. In this project, we quantified immune cell infiltrates in the angiosarcoma tumor microenvironment. Unsupervised clustering was applied to reveal prognostically significant immune phenotypes. Proteomic profiling of 88 angiosarcoma samples (54 primary tissue, 17 local relapse tissue, and 17 metastatic tissue), 20 benign control tissues and 9 pooled groups was performed by LC–MS/MS to compare various AS subtypes, as well as up- and downregulated pathways between immune cell clusters.
HostingRepository	PRIDE
AnnounceDate	2026-03-14
AnnouncementXML	Submission_2026-03-13_21:46:15.966.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Proteomics Facility
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	iodoacetamide derivatized residue
Instrument	timsTOF Pro 2

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-11-10 02:17:07	ID requested
⏵ 1	2026-03-13 21:46:16	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Sarcoma, angiosarcoma, tumor immune environment, tumor microenvironment

submitter keyword: Sarcoma, angiosarcoma, tumor immune environment, tumor microenvironment

Contact List

Prof. Dr. Alexander Quaas
contact affiliation	Institute of Pathology, University Hospital Cologne, Cologne, Germany
contact email	alexander.quaas@uk-koeln.de
lab head
Proteomics Facility
contact affiliation	CECAD Research Center
contact email	proteomics-facility@uni-koeln.de
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD070528
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD070528

PRIDE project URI

Repository Record List

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