PXD070477 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Phosphoproteomic analysis for the detection of the EMX2-EGFR signaling network controlling glioblastoma progression |
| Description | Glioblastoma (GB), the most frequent and aggressive primary adult brain tumour, remains an incurable disease and new therapeutic approaches are needed to improve patient care. The transcription factor EMX2 plays a key role in modulating the balance between neurogenesis and astrogenesis during brain development. This transcription factor has also been involved in tumor growth. To further investigate the role of EMX2 in GB, we used an EMX2-inducible U87 cells. Multi-omics analyses (ChIPseq, transcriptome, proteome and phosphoproteome) were performed in U87 cells expressing EMX2 or not in a timely delineated manner. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-13 |
| AnnouncementXML | Submission_2025-11-13_08:41:49.190.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Luc Negroni |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-11-07 14:37:17 | ID requested | |
| ⏵ 1 | 2025-11-13 08:41:49 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Human, phosphoproteome, Glioblastoma |
Contact List
| Jean Mosser |
|---|
| contact affiliation | INSERM U1242, University of Rennes, Rennes France. |
| contact email | jean.mosser@univ-rennes.fr |
| lab head | |
| Luc Negroni |
|---|
| contact affiliation | CNRS |
| contact email | lnegroni@unistra.fr |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD070477
- Label: PRIDE project
- Name: Phosphoproteomic analysis for the detection of the EMX2-EGFR signaling network controlling glioblastoma progression
