PXD070384

PXD070384 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The Nicotinamide Salvage Pathway is a Unique Metabolic target in High-Risk MDS Stem Cells
Description	High-risk myelodysplastic syndrome (HR-MDS) is an incurable malignant clonal disorder originating in hematopoietic stem and progenitor cells (HSPC). This study demonstrates that HR-MDS HSPCs have a significant upregulation of metabolic proteins required for glycolysis, citric acid cycle, and oxidative phosphorylation.
HostingRepository	PRIDE
AnnounceDate	2026-07-13
AnnouncementXML	Submission_2026-07-13_11:09:51.949.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alexandra Crook
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-11-05 17:28:08	ID requested
⏵ 1	2026-07-13 11:09:52	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: timsTOF SCP,human

submitter keyword: timsTOF SCP,human

Contact List

Eric M. Pietras
contact affiliation	Division of Hematology, Department of Medicine, University of Colorado Anschutz, Aurora, CO, USA
contact email	eric.pietras@cuanschutz.edu
lab head
Alexandra Crook
contact affiliation	University of Colorado
contact email	alexandra.crook@cuanschutz.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD070384
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD070384

PRIDE project URI

Repository Record List

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