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PXD070331

PXD070331 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePlasma Multi-Omics in Response to Long-Term Low-Dose Ionizing Radiation
DescriptionThis study performed quantitative plasma proteomics on 5 radiation-exposed workers and 5 healthy controls using high-resolution LC-MS/MS (Orbitrap Exploris 480). Proteins were extracted, reduced, alkylated, trypsin-digested, and analyzed in DDA mode. Data was processed with Spectronaut 14 using dynamic iRT prediction, 1% FDR filtering, and top3 peptide quantification. Differentially expressed proteins between groups were identified using Welch's ANOVA (p<0.05, FC>1.5) to investigate the impact of occupational radiation exposure.
HostingRepositoryiProX
AnnounceDate2025-11-05
AnnouncementXMLSubmission_2025-11-04_17:51:15.287.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZhongwei Chang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-11-04 17:50:38ID requested
12025-11-04 17:51:15announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Ionizing radiation, Metabolomics, Lipidomics, Proteomics, Co-occurrence network
Contact List
Xinjun Wang
contact affiliationAffiliated Suzhou Hospital ofNanjing Medical University, Suzhou Municipal Hospital
contact emailxjwang16@fudan.edu.cn
lab head
Zhongwei Chang
contact affiliationHuaihe Hospital of Henan University
contact email2628177895@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI