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PXD070326

PXD070326 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleN-terminome data for "A single-amino-acid cleavage controls global mitochondrial complex integrity"
DescriptionMitochondrial proteostasis depends on precise N-terminal processing of imported precursor proteins, and defects in this maturation step are implicated in severe human diseases, yet the functional impact in humans remain unclear. This HUNTER N-terminome dataset identify over one hundred human ICP55 substrates in mitochondria isolated from wt and ICP55-deficient HEK293T cells
HostingRepositoryPRIDE
AnnounceDate2026-07-22
AnnouncementXMLSubmission_2026-07-22_06:34:15.853.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPitter Huesgen
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListacetylated residue
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-11-04 17:00:01ID requested
12026-07-22 06:34:16announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: A single-amino-acid cleavage controls global mitochondrial complex integrity
Contact List
Prof. Dr. Pitter Huesgen
contact affiliationUniversity of Freiburg Faculty of Biology Biochemistry and Functional Proteomics Schänzlestrasse 1 79104 Freiburg Germany
contact emailpitter.huesgen@biologie.uni-freiburg.de
lab head
Pitter Huesgen
contact affiliationUniversity of Freiburg Faculty of Biology Biochemistry and Functional Proteomics
contact emailpitter.huesgen@biologie.uni-freiburg.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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