⮝ Full datasets listing
PXD070259
PXD070259 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Lipid Droplet–Mediated Depletion of DAG in the TGN Impairs IFNGR1 Membrane Localization and Anti-Tumor Immunity |
| Description | Lipid droplets (LDs) are dynamic organelles that regulate cellular metabolism, yet their role in tumor immune evasion remains unclear. Here, we demonstrate that LDs in cancer cells suppress anti-tumor immunity by impairing the membrane location of interferon-gamma receptor 1 (IFNGR1). |
| HostingRepository | iProX |
| AnnounceDate | 2025-11-03 |
| AnnouncementXML | Submission_2025-11-03_17:01:31.742.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Lingyan Xu |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-11-03 17:01:05 | ID requested | |
| ⏵ 1 | 2025-11-03 17:01:32 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Lipid droplets,FITM2, IFNGR1, colon cancer |
Contact List
| Yanhong Gu | |
|---|---|
| contact affiliation | The First Affiliated Hospital of Nanjing Medical University |
| contact email | guyhphd@163.com |
| lab head | |
| Lingyan Xu | |
| contact affiliation | The First Affiliated Hospital of Nanjing Medical University |
| contact email | xulingyan1994@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
