PXD070232

PXD070232 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Exploring Proteomic Differences in PBMCs for Sex-Specific Insights into Alzheimer’s Disease
Description	This study investigated sex-dependent proteomic alterations in peripheral blood mononuclear cells (PBMCs) from Alzheimer’s disease (AD) patients. Quantitative DIA-based proteomics revealed both shared and sex-specific pathways, including complement activation, coagulation, and metabolic processes. These findings highlight systemic immune and metabolic remodeling in AD that differ between males and females.
HostingRepository	PRIDE
AnnounceDate	2026-01-15
AnnouncementXML	Submission_2026-01-15_10:17:22.310.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD070232
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Takako Takaku
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Astral

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-11-03 09:23:20	ID requested
⏵ 1	2026-01-15 10:17:22	announced

Publication List

10.6019/PXD070232;
10.17912/MICROPUB.BIOLOGY.001922;

10.6019/PXD070232;

10.17912/MICROPUB.BIOLOGY.001922;

Keyword List

submitter keyword: None

submitter keyword: None

Contact List

Colin K.
contact affiliation	Department of Biomedical Sciences, University of North Dakota, Grand Forks, ND, USA
contact email	colin.combs@und.edu
lab head
Takako Takaku
contact affiliation	Department of Biomedical Sciences, University of North Dakota, Grand Forks, ND, USA
contact email	takako.takaku@und.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD070232
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD070232

PRIDE project URI

Repository Record List

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