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PXD070215

PXD070215 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePISA-based thermal proteome profiling of human liver tissue exposed to environmental pollutants
DescriptionThis study applied the Proteome Integral Solubility Alteration (PISA) approach combined with DIA-MS to characterize protein stability changes in human liver tissue exposed to environmental pollutants, including BPA, PAH, PFOS, and TMP. The work provides a proteome-wide overview of pollutant-induced thermal stability alterations and identifies potential protein targets involved in environmental hepatotoxicity.
HostingRepositoryiProX
AnnounceDate2025-11-03
AnnouncementXMLSubmission_2025-11-03_00:37:27.859.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYawen Tian
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-11-03 00:36:54ID requested
12025-11-03 00:37:28announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Human, Liver, PISA, Thermal proteome profiling, DIA, timsTOF Pro2
Contact List
Jiayin Dai
contact affiliationShanghai Jiao Tong University
contact emaildaijy65@sjtu.edu.cn
lab head
Yawen Tian
contact affiliationShanghai Jiao Tong University
contact emailyawentian@sjtu.edu.cn
dataset submitter
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