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PXD070068

PXD070068 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCryo-EM Structures of Biopsy-derived TTR Filaments in Hereditary Transthyretin Amyloidosis.
DescriptionWe examined the structure of transthyretin filaments extracted from the vitreous humor of an individual with ATTRv-F64S by cryo-electron microscopy. Mass spectrometry was used to confirmed the presence of both mutant and wild-type transthyretin in the filaments.
HostingRepositoryiProX
AnnounceDate2025-10-30
AnnouncementXMLSubmission_2025-12-31_00:27:45.189.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYuxin Zheng
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-29 20:45:09ID requested
12025-12-31 00:27:45announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Hereditary transthyretin amyloidosis, Transthyretin filaments, Vitreous humor
Contact List
Yang Shi
contact affiliationZhejiang University
contact emailyshi22@zju.edu.cn
lab head
Yuxin Zheng
contact affiliationZhejiang University
contact emailyxzheng98@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI