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PXD069995

PXD069995 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomics of the brain and retina presents early hallmarks of Alzheimer’s disease
DescriptionWe performed proteomic profiling of the brain and retina in 3xTg-AD mouse model of Alzheimer's disease at one month of age to uncover early retinal signatures that may precede disease manifestations.
HostingRepositoryPRIDE
AnnounceDate2026-06-08
AnnouncementXMLSubmission_2026-06-07_17:53:45.203.xml
DigitalObjectIdentifierhttps://doi.org/10.6019/PXD069995
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterArtjola Puja
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-28 14:09:03ID requested
12026-06-07 17:53:46announced
Publication List
Puja A, McNeel R, Xu R, Zhu S, Hansman D, Du J, Early proteomic signatures of Alzheimer's disease in the retina and brain of 3xTg-AD mice. Front Cell Dev Biol, 14():1827348(2026) [pubmed]
10.6019/PXD069995;
10.3389/fcell.2026.1827348;
Keyword List
submitter keyword: Alzheimer's disease
Retina
Brain
neurodegenerative diseases
3xTg-AD
Contact List
Jianhai Du
contact affiliationWest Virginia University
contact emailjianhai.du@hsc.wvu.edu
lab head
Artjola Puja
contact affiliationGraduate student
contact emailap00093@mix.wvu.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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