PXD069979 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic Analysis of the Differential Response of Pseudomonas aeruginosa and Staphylococcus aureus to Lacticaseibacillus rhamnosus Cell-Free Supernatant and Lactic Acid |
| Description | This project investigates the proteomic response of Pseudomonas aeruginosa PAO1 and Staphylococcus aureus to postbiotic metabolites derived from Lacticaseibacillus rhamnosus. Bacterial cultures were exposed to sub-MIC concentrations of L. rhamnosus cell-free supernatant (CFS) or lactic acid (LA) for 6 h, and intracellular proteins were extracted for quantitative label-free proteomics using HPLC–MS/MS. The dataset includes RAW mass spectrometry data and MaxQuant output files. The aim of this study is to compare stress responses triggered by complex postbiotic mixtures versus LA alone, focusing on antimicrobial and antibiofilm potential. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-05 |
| AnnouncementXML | Submission_2026-01-04_16:38:56.253.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Marta Bianchi |
| SpeciesList | scientific name: Staphylococcus aureus; NCBI TaxID: NEWT:1280; scientific name: Pseudomonas aeruginosa PAO1; NCBI TaxID: NEWT:208964; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-10-28 06:18:18 | ID requested | |
| ⏵ 1 | 2026-01-04 16:38:57 | announced | |
Publication List
Keyword List
| submitter keyword: Probiotics |
| Postbiotics |
| Antimicrobials |
| Cell-free supernatants |
| L. rhamnosus |
| P. aeru-ginosa |
| S. aureus |
| Proteomics. |
Contact List
| Kevin Kavanagh |
|---|
| contact affiliation | Department of Biology, Maynooth University, Maynooth, Co. Kildare, Ireland; |
| contact email | Kevin.Kavanagh@mu.ie |
| lab head | |
| Marta Bianchi |
|---|
| contact affiliation | Università di Pisa |
| contact email | marta.bianchi@phd.unipi.it |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD069979 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD069979
- Label: PRIDE project
- Name: Proteomic Analysis of the Differential Response of Pseudomonas aeruginosa and Staphylococcus aureus to Lacticaseibacillus rhamnosus Cell-Free Supernatant and Lactic Acid
