⮝ Full datasets listing
PXD069937
PXD069937 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The Lip-MS experiment by Azeliragon and MurA |
| Description | The drug treatment group with Azeliragon and the untreated control group were both subjected to limited proteolysis using proteinase K. Because Azeliragon binds to the target protein, certain regions of the protein in the drug group are "protected" from being cut by the enzyme, unlike in the control group. High-resolution mass spectrometry was then used to detect and quantify peptides in both groups. By comparing peptide levels, we can pinpoint where Azeliragon binds, identifying potential antibacterial targets. |
| HostingRepository | iProX |
| AnnounceDate | 2025-10-27 |
| AnnouncementXML | Submission_2025-10-27_01:28:56.015.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Junhua Ma |
| SpeciesList | scientific name: Staphylococcus aureus; NCBI TaxID: 1280; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-10-27 01:28:42 | ID requested | |
| ⏵ 1 | 2025-10-27 01:28:56 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Azeliragon, Lip-MS |
Contact List
| Zhijian Yu | |
|---|---|
| contact affiliation | Shenzhen Nanshan People’s Hospital |
| contact email | yuzhijiansmu@163.com |
| lab head | |
| Junhua Ma | |
| contact affiliation | Shenzhen Nanshan People’s Hospital |
| contact email | MMjunhua@outlook.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
