PXD069867 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | One way or another: Differential impact of pharmacologic inhibitors on extracellular vesicles derived from resting neutrophils |
| Description | We performed a systematic investigation of seven pharmacologic inhibitors (calpeptin, D-pantethine, Y27632, cytochalasin D, GW4869, R5421, and Nexinhib20) on quantitative and qualitative EV properties derived from resting neutrophils. We measured EV numbers, size distribution, total lipid, protein, and RNA content. We also analyzed the EV morphology by cryo-EM and EV cargo qualitatively by mass spectrometry and RNA sequencing. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-06-15 |
| AnnouncementXML | Submission_2026-06-14_16:21:45.274.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Viktoria Szeifert |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Eclipse |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-10-23 20:32:37 | ID requested | |
| ⏵ 1 | 2026-06-14 16:21:46 | announced | |
Publication List
| 10.1038/s41598-026-48570-8; |
| Szeifert V, Szeifert A, Arnold WR, Terasaki A, Bhatnagar K, Okwan-Duodu D, Comparative analysis of extracellular vesicles released from resting neutrophils under distinct pharmacological inhibition. Sci Rep, 16(1):(2026) [pubmed] |
Keyword List
| submitter keyword: EV, exosome,PMN EV MS, neutrophil, extracellular vesicles |
Contact List
| Derick Okwan-Doudu |
|---|
| contact affiliation | Assistant Professor |
| contact email | dokwan@stanford.edu |
| lab head | |
| Viktoria Szeifert |
|---|
| contact affiliation | Postdoctroal Fellow |
| contact email | szeivik@stanford.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD069867 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD069867
- Label: PRIDE project
- Name: One way or another: Differential impact of pharmacologic inhibitors on extracellular vesicles derived from resting neutrophils
