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PXD069860

PXD069860 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePLK3 inhibitors treatment induces viral proteins expression in active reservoir from ART-treated individuals
DescriptionCD4+ T cells were individually isolated from twenty ART-treated PLWH (each donor provided 50 ml blood; all viral loads <50 copies/mL), and treated with PLK3 inhibitors(GW843682X and NMS-P937). At 2 days post-treatment, cell lysates (from 2  108 total cells) were pooled and subjected to IP with anti-gp120, anti-Gag, anti-Vpr, or IgG antibodies, followed by LC-MS to detect gp120, Gag, and Vpr proteins in precipitates.
HostingRepositoryiProX
AnnounceDate2025-10-24
AnnouncementXMLSubmission_2025-10-23_20:09:33.790.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLi Zhao
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 240
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-23 20:09:14ID requested
12025-10-23 20:09:34announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: PLK3, inhibitor, active reservoir
Contact List
Guoxin Liang
contact affiliationThe First Hospital of China Medical University
contact emailgxliang@cmu.edu.cn
lab head
Li Zhao
contact affiliationThe First Hospital of China Medical University
contact emailzhaoliyeah@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI