PXD069851

PXD069851 is an original dataset announced via ProteomeXchange.

Title	Bovine Corpus Luteum Proteomics during Different Reproductive and Physiological Stages
Description	Corpus luteum (CL) is an endocrine structure that undergoes substantial changes over short intervals during the bovine reproductive (estrous) cycle. These changes are regulated by a vast array of signaling molecules, mainly proteins, that govern reproduction. We collected a comprehensive set of CLs from non-pregnant (days 1–2, 3–4, 5–7, 8–12, 13–17, and >18) and pregnant (months 1–2, 3–4, 5–6, and >7) cows, enabling a detailed characterization of temporal changes in CL biology. While previous studies have focused on a limited number of proteins, we employed a broader approach to exploring additional proteins potentially involved in CL regulation across different stages. Using high-resolution mass spectrometry (HR-LC-MS/MS), we identified approximately 3,783 individual proteins. These proteins may be useful for research in species where access to well-characterized CL tissue is limited. Our findings indicate diverse changes in protein expression across groups, highlighting proteomic patterns that may reflect key processes of bovine reproduction, particularly during the transition toward regression, a critical period that influences whether the CL is maintained to support pregnancy or undergoes regression.
HostingRepository	PRIDE
AnnounceDate	2026-02-19
AnnouncementXML	Submission_2026-02-19_04:58:39.340.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Christina Ludwig
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: NEWT:9913;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-10-23 15:24:10	ID requested
⏵ 1	2026-02-19 04:58:39	announced

Dataset with its publication pending

submitter keyword: None

Christina Ludwig
contact affiliation	Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University Munich (TUM) Gregor-Mendel-Straße 4 85354 Freising GERMANY
contact email	tina.ludwig@tum.de
lab head
Christina Ludwig
contact affiliation	TU Munich
contact email	tina.ludwig@tum.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD069851

PRIDE project URI

• PRIDE
  1. PXD069851
     1. Label: PRIDE project
     2. Name: Bovine Corpus Luteum Proteomics during Different Reproductive and Physiological Stages