PXD069850

PXD069850 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomics of Geobacter sulfurreducens strain PCA in different culture media
Description	Electroactive Geobacter bacteria drive critical environmental metal transformations that are of interest for metal bioremediation and recovery from wastes. Most of our understanding of these processes comes from laboratory-based studies under conditions that mimic the natural Geobacter environment. Our study identifies that small differences in the sodium ionic strength of cultivation media affect cell wall phenotypes and uranium detoxification mechanisms by Geobacter sulfurreducens. Quantitative proteomics revealed that proteins associated with the cell envelope and extracellular electron transfer functions were also differentially expressed in these media.
HostingRepository	PRIDE
AnnounceDate	2026-09-07
AnnouncementXML	Submission_2026-09-07_04:24:09.741.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Gemma Reguera
SpeciesList	scientific name: Geobacter sulfurreducens PCA; NCBI TaxID: NEWT:243231;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2025-10-23 15:12:09	ID requested
⏵ 1	2026-09-07 04:24:11	announced

Clark MM, Kashefi K, Reguera G, Cation-driven envelope dynamics modulate outer membrane vesiculation and extracellular electron transfer in Geobacter. Nat Commun, 17(1):(2026) [pubmed]

10.1038/s41467-026-74523-w;

submitter keyword: medium, DIA,Geobacter sulfurreducens, ionic strength, LC-MS/MS

Gemma Reguera
contact affiliation	Reguera Lab, Department of Microbiology, Genetic, and Immunology, Michigan State University, Michigan, USA
contact email	reguera@msu.edu
lab head
Gemma Reguera
contact affiliation	Michigan State University
contact email	reguera@msu.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD069850

PRIDE project URI

• PRIDE
  1. PXD069850
     1. Label: PRIDE project
     2. Name: Quantitative proteomics of Geobacter sulfurreducens strain PCA in different culture media