PXD069806 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | GFP-Tensin 1 phosphoproteomics upon sodium arsenite treatment in U2OS cells |
| Description | Tensin 1 (TNS1) is a key component of integrin adhesion and plays a key role in linking the actin cytoskeleton with the ECM through interaction with integrin heterodimers. TNS1 forms functional and reversible condensates in cells in response to different extracellular stimuli that act as reservoirs of adhesion components. Here we analysed the role of phosphorylation on TNS1 condensation. Using phosphoproteomics of affinity-purified GFP-TNS1 from control and sodium arsenite-treated U2OS cells, we identify the phosphosites regulating TNS1 condensation. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-24 |
| AnnouncementXML | Submission_2026-04-24_06:24:51.831.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Michal Dibus |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-10-22 18:45:57 | ID requested | |
| ⏵ 1 | 2026-04-24 06:24:52 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: phosphorylation, protein condensation, integrin adhesions, phase separation,Tensin 1 |
Contact List
| Johanna Ivaska |
|---|
| contact affiliation | University of Turku, Turku Bioscience |
| contact email | joivaska@utu.fi |
| lab head | |
| Michal Dibus |
|---|
| contact affiliation | University of Turku, Turku Bioscience |
| contact email | michal.dibus@utu.fi |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD069806
- Label: PRIDE project
- Name: GFP-Tensin 1 phosphoproteomics upon sodium arsenite treatment in U2OS cells
