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PXD069800

PXD069800 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMice osteoclast-derived apoptotic bodies LC-MS/MS
DescriptionWe design OsteoSAVE, a peptide-based nanoparticle integrating a cathepsin K (CTSK)-cleavable linker, a bone-targeting motif, and a self-assembling biphenyl core. Upon CTSK-mediated hydrolysis, OsteoSAVE transforms into nanofibers within osteoclast lysosomes, inducing apoptosis and releasing apoptotic bodies.
HostingRepositoryiProX
AnnounceDate2025-10-22
AnnouncementXMLSubmission_2025-10-22_18:24:36.396.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPeng Zhang
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 240
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-22 18:18:52ID requested
⏵ 12025-10-22 18:24:36announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Mice osteoclast-derived apoptotic bodies LC-MS/MS
Contact List
Huaimin Wang
contact affiliationWestlake University
contact emailwanghuaimin@westlake.edu.cn
lab head
Peng Zhang
contact affiliationWestlake University
contact emailzhangpeng46@westlake.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI

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