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PXD069667

PXD069667 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of healthy human Aqueous Humour, Anterior Lens Capsules, and Crystalline Lenses
DescriptionParticipants were recruited from the Ophthalmology Department among patients scheduled for cataract surgery. Patients were stratified into four distinct groups based on their clinical profiles. ARC group (Age-Related Cataract) included individuals over the age of 75 without a history of diabetes; DC group (Diabetic cataract) included individuals un-der the age of 65 with a known diagnosis of type 1 or type 2 diabetes mellitus; PVC group (Post-Vitrectomy cataract) included individuals of any age, without diabetes, who had undergone vitrectomy with gas tamponade for retinal detachment within the previous 12 months and who had clear lens prior to vitrectomy; and the control group included indi-viduals under the age of 60, without diabetes, who underwent clear lens extraction for re-fractive reasons.
HostingRepositoryPRIDE
AnnounceDate2025-12-01
AnnouncementXMLSubmission_2025-11-30_22:16:06.230.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMartina Samiotaki
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-20 06:28:26ID requested
12025-11-30 22:16:07announced
Publication List
Karakosta C, Samiotaki M, Bisoukis A, Bougioukas KI, Panayotou G, Kyriakidou N, Moschou K, Moschos MM, Comparative Proteomic Analysis of Aqueous Humor, Anterior Lens Capsules, and Crystalline Lenses in Different Human Cataract Subtypes Versus Healthy Controls. Proteomes, 13(4):(2025) [pubmed]
10.3390/proteomes13040062;
Keyword List
submitter keyword: Anterior Lens,Human Aqueous Humour, Capsules, Proteomics
Contact List
Christina Karakosta
contact affiliationSchool of Medicine, National and Kapodistrian University of Athens, Greece.
contact emailchristine.karakosta@gmail.com
lab head
Martina Samiotaki
contact affiliationProtein Analysis Laboratory B.S.R.C. "Alexander Fleming", Alexander Fleming Street 34 16672, Vari, Greece
contact emailsamiotaki@fleming.gr
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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