PXD069503
PXD069503 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Omics Profiling of Patients with Obstructive Sleep Apnoea Reveals Risks of Diabetes Mellitus and Cardiovascular Diseases |
| Description | Obstructive sleep apnoea (OSA), a type of chronic intermittent hypoxia with increasing global prevalence, constitutes a multisystemic disorder often associated with cardiovascular and metabolic disorders.In total, 142 plasma samples were acquired: 50 from controls (CON), 45 from mild/moderate OSA (M-OSA) patients, and 47 from severe OSA (S-OSA) patients.Proteomic and metabolic signatures significantly differed among S-OSA, M-OSA, and CON samples.Omics analysis revealed the characteristics of OSA and uncovered potential mechanisms by which diabetes mellitus and cardiovascular disease risks are increased in OSA. These results might also provide new diagnostic biomarkers for OSA and the identification of severe cases. |
| HostingRepository | iProX |
| AnnounceDate | 2025-10-16 |
| AnnouncementXML | Submission_2025-10-15_18:44:27.612.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jieqiong Li |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-10-15 18:44:03 | ID requested | |
| ⏵ 1 | 2025-10-15 18:44:28 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Obstructive Sleep Apnoea, Metabolomic and Proteomic, Diagnosis, Diabetes mellitus, Cardiovascular diseases |
Contact List
| Jieqiong Li | |
|---|---|
| contact affiliation | Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University |
| contact email | jieqiongli2010@163.com |
| lab head | |
| Jieqiong Li | |
| contact affiliation | Medical Research Center, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University |
| contact email | jieqiongli2010@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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