PXD069459
PXD069459 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Intratumoral vaccination via degradation-coupled-presentation with restored antitumor immunity |
| Description | To validate changes in the MHC-I restricted immunopeptidome of murine and human cancer cells following degrader treatment, specifically focusing on the presentation of specific target antigen sequences and tracking the overall quality of antigen peptides. |
| HostingRepository | iProX |
| AnnounceDate | 2025-10-14 |
| AnnouncementXML | Submission_2025-10-14_18:53:45.536.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yicong Ma |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-10-14 18:53:25 | ID requested | |
| ⏵ 1 | 2025-10-14 18:53:46 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Targeted membrane protein degradation, Covalent nanobody, Tumor immunogenicity |
Contact List
| Peng Chen | |
|---|---|
| contact affiliation | College of Chemistry and Molecular Engineering, Peking University |
| contact email | pengchen@pku.edu.cn |
| lab head | |
| Yicong Ma | |
| contact affiliation | Academy for Advanced Interdisciplinary Studies, Peking University |
| contact email | mayicong@outlook.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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