PXD069327 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The Human Lens Fiber Cytoskeletome Reveals Neuronal Signatures, and the presence of Chaperonins, Signaling, Proteasome and Redox Regulators |
| Description | Morphogenesis, growth, shape, mechanics, and transparency of the ocular lens critically depend on cytoskeletal networks and cell adhesive interactions. However, the molecular composition of these cellular components of lens fibers remains to be defined in depth. This study is aimed at providing an unbiased and comprehensive characterization of cytoskeletal and cytoskeleton-associated proteins in human lens fibers. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-05-25 |
| AnnouncementXML | Submission_2026-05-24_16:25:49.003.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD069327 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Nik Skiba |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-10-10 11:00:34 | ID requested | |
| ⏵ 1 | 2026-05-24 16:25:49 | announced | |
Publication List
| Maddala R, Lankford LK, Skiba NP, Rao PV, The Human Lens Fiber Cytoskeletome Reveals Neuronal Signatures and the Presence of Chaperonins, Proteasome, Signaling, and Redox Regulators. Invest Ophthalmol Vis Sci, 67(5):45(2026) [pubmed] |
| 10.6019/PXD069327; |
| 10.1167/iovs.67.5.45; |
Keyword List
| submitter keyword: cytoskeleton, lens,human, proteome |
Contact List
| Ponugoti V. Rao |
|---|
| contact affiliation | Duke University Eye Center |
| contact email | p.rao@duke.edu |
| lab head | |
| Nik Skiba |
|---|
| contact affiliation | Duke University |
| contact email | skibanik@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD069327 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD069327
- Label: PRIDE project
- Name: The Human Lens Fiber Cytoskeletome Reveals Neuronal Signatures, and the presence of Chaperonins, Signaling, Proteasome and Redox Regulators
