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PXD069263

PXD069263 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCD8+ T cells are primed by cDC1 and exacerbate tau-mediated neurodegeneration
DescriptionMHC-I and MHC-II peptidomes of brain, spleen, and deep cervical lymph nodes (dCLN) from control and P301S tau transgenic 64 mice expressing human APOE4. Data were collected in ddaPASEF mode on a timsTOF Ultra 2.
HostingRepositoryMassIVE
AnnounceDate2026-06-29
AnnouncementXMLSubmission_2026-06-29_13:06:50.940.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterCheryl Lichti
SpeciesList scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationListL-methionine sulfoxide; iodoacetamide - site C
InstrumenttimsTOF Ultra 2
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-09 15:14:36ID requested
⏵ 12026-06-29 13:06:51announced
Publication List
no publication
Keyword List
submitter keyword: immunopeptidomics, neurodegeneration, tauopathy, brain, dCLN, DatasetType:Proteomics
Contact List
David Holtzman
contact affiliationWashington University School of Medicine in St. Louis
contact emaildholtzman@wustl.edu
lab head
Cheryl Lichti
contact affiliationWashington University in St. Louis
contact emailclichti@wustl.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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