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PXD069233

PXD069233 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic Signatures of Dental Enamel
DescriptionExposure to excessive fluoride can lead to dental enamel hypomineralization characterized by retention of enamel matrix proteins(EMPs). However, the types and functions of EMPs from different fluoride exposure pathways remains elusive. This study selected moderate-to-severe coal-fired dental fluorosis enamel(CDF), water-drinking dental fluorosis enamel(WDF) and healthy permanent dental enamel (H) from the residents (local until age 12). EMPs were extracted, digested, and analyzed via nanoLC-HRMS/MS, followed by database searching and bioinformatics.
HostingRepositoryiProX
AnnounceDate2025-10-01
AnnouncementXMLSubmission_2026-07-01_01:01:02.787.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterNa Yang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 240
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-10-09 01:39:57ID requested
12026-07-01 01:01:03announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Mature dental enamel, Enamel Hypomineralization, Enamel Matrix Proteins, Proteomic
Contact List
Chenglong Tu
contact affiliationGuizhou Medical University
contact emailchengscience@163.com
lab head
Na Yang
contact affiliationGuizhou Medical University
contact emailhuaxueyangna@126.com
dataset submitter
Full Dataset Link List
iProX dataset URI