PXD069144

PXD069144 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Smooth muscle cell spheroids as 3D model of phenotypic plasticity and matrix deposition revealed by 2D-3D proteomics
Description	Our study aims to compare 2D adherent and 3D floating (spheroid) cell cultures of in the context of cellular physiology and in atherosclerosis modelling. Here, we utilize vascular smooth muscle cells from rat aorta to profile 2D and 3D proteomes.
HostingRepository	PRIDE
AnnounceDate	2026-09-07
AnnouncementXML	Submission_2026-09-06_22:34:55.270.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ulrike Resch
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: NEWT:10116;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-10-05 11:33:14	ID requested
1	2026-09-06 16:15:29	announced
2	2026-09-06 22:31:16	announced	2026-09-07: Updated project metadata.
⏵ 3	2026-09-06 22:34:56	announced	2026-09-07: Updated project metadata.

Publication List

Hesse J, Resch U, G, ö, rtz L, Lang S, Batool R, Saradar S, Schoof P, Gehlweiler K, Zouikova D, Jashnieh P, Fernandes Velosa R, Hotzel-Hacker N, Suzuki F, Bayraktar S, Cappallo M, Schmidt V, Ebbert L, B, ü, low MH, Kucharowski N, Laakkonen EK, Kr, ü, ger M, Sengle G, Chadt A, Lichtenberg A, Aubin H, Weber E, Smooth muscle cell spheroids as 3D model of phenotypic plasticity and matrix deposition revealed by 2D-3D proteomics. Sci Rep, 16(1):(2026) [pubmed]
10.1038/s41598-026-61834-7;

Hesse J, Resch U, G, ö, rtz L, Lang S, Batool R, Saradar S, Schoof P, Gehlweiler K, Zouikova D, Jashnieh P, Fernandes Velosa R, Hotzel-Hacker N, Suzuki F, Bayraktar S, Cappallo M, Schmidt V, Ebbert L, B, ü, low MH, Kucharowski N, Laakkonen EK, Kr, ü, ger M, Sengle G, Chadt A, Lichtenberg A, Aubin H, Weber E, Smooth muscle cell spheroids as 3D model of phenotypic plasticity and matrix deposition revealed by 2D-3D proteomics. Sci Rep, 16(1):(2026) [pubmed]

10.1038/s41598-026-61834-7;

Keyword List

submitter keyword: Smoot muscle cell
Spheroids
3D cell culture
LC-MS/MS

submitter keyword: Smoot muscle cell

Spheroids

3D cell culture

LC-MS/MS

Contact List

Ulrike Resch
contact affiliation	Ulrike Resch, DI. Dr. rer. nat. Medical University of Vienna Center of Physiology and Pharmacology Department of Vascular Biology and Thrombosis Research Schwarzspanierstraße 17/I A- 1090 Vienna, Austria ORCID-ID:0000-0002-8380-9555
contact email	ulrike.resch@meduniwien.ac.at
lab head
Ulrike Resch
contact affiliation	Medical University of Vienna, Deptartment of Vascular Biology and Thrombosis Research
contact email	ulrike.resch@meduniwien.ac.at
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD069144
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD069144

PRIDE project URI

Repository Record List

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