PXD069102

PXD069102 is an original dataset announced via ProteomeXchange.

Title	Proteomic profiling of New Zealand endemic Porphyra/Pyropia (karengo) seaweeds: A predictive framework for functional food applications
Description	Porphyra/Pyropia seaweeds are promising sources for functional foods development, offering a rich macro- and micronutrient profiles. In New Zealand (NZ), endemic Porphyra/Pyropia species (karengo), exhibit considerable variability driven by geography, seasonality, and climate, which may influence their nutritional quality. Despite their use as traditional foods, the NZ Porphyra/Pyropia remain underutilized commercially, in part due to the lack of biomolecular characterisation, particularly their bioactive protein components, hindering evidence-based species selection for seaweed farming commercialisation and functional food development. This study presents the first proteomic characterization of three NZ Porphyra/Pyropia species: Pyropia virididentata, Pyropia cinnamomea, and Porphyra GRB complex. Mass spectrometry-based proteomics analysis identified differences in the phycobiliprotein composition among the species, with the Porphyra GRB complex containing higher levels of phycocyanin. Using the protein sequence information, in silico gastrointestinal digestion analysis predicted that phycobiliproteins from NZ Porphyra/Pyropia seaweeds can potentially release bioactive peptides capable of inhibiting angiotensin-converting enzyme (ACE) and dipeptidyl peptidase-IV (DPP-IV) activities. Sequence-based allergenicity prediction indicated possible cross-reactivity between NZ Porphyra/Pyropia β-phycoerythrin and β-phycocyanin against the β-phycocyanin allergen from spirulina, which is associated with a low incidence of allergy. Proximate analysis revealed that NZ Porphyra/Pyropia seaweeds have high protein (26–30.2 %) and carbohydrate (48.3–50.9 %) contents, and low fat and free sugar levels. Amino acid profiling further showed that NZ Porphyra/Pyropia seaweeds are relatively rich in sulphur-containing amino acids and umami-associated amino acids. Overall, these findings highlight the potential of NZ Porphyra/Pyropia seaweeds as a novel plant-based protein source for functional food applications.
HostingRepository	PRIDE
AnnounceDate	2026-02-09
AnnouncementXML	Submission_2026-02-09_00:47:26.989.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chee Fan Tan
SpeciesList	scientific name: Bangiaceae; NCBI TaxID: NEWT:31345;
ModificationList	acetylated residue; monohydroxylated residue; deaminated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2025-10-02 17:10:21	ID requested
⏵ 1	2026-02-09 00:47:27	announced

10.1016/J.FUFO.2026.100938;

submitter keyword: None

Bi Xuezhi
contact affiliation	Senior Principal Scientist I,Bioprocessing Technology Institute, A*Star, Singapore Adjunct Associate Professor, Duke-NUS Medical School, Singapore Adjunct Associate Professor,Singapore Institute of Technology, Singapore
contact email	bi_xuezhi@a-star.edu.sg
lab head
Chee Fan Tan
contact affiliation	Agency for Technology, Science and Research
contact email	tancf@bti.a-star.edu.sg
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD069102

PRIDE project URI

• PRIDE
  1. PXD069102
     1. Label: PRIDE project
     2. Name: Proteomic profiling of New Zealand endemic Porphyra/Pyropia (karengo) seaweeds: A predictive framework for functional food applications