PXD068991
PXD068991 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Microglial NLRC5 Drives Lysosomal Dysfunction to Disrupt Autophagic Flux and Promote Post-Stroke Neuroinflammation |
| Description | To further elucidate the molecular mechanisms by which microglial NLRC5 exacerbates post-stroke inflammation, we performed proteomic profiling of primary microglia isolated from WT and Nlrc5 KO mice following OGD/R treatment. |
| HostingRepository | iProX |
| AnnounceDate | 2025-09-30 |
| AnnouncementXML | Submission_2025-10-08_17:52:40.613.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Siyi Xu |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Ultra |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-09-30 03:17:50 | ID requested | |
| ⏵ 1 | 2025-10-08 17:52:41 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: WT, NLRC5 KO, Primary microglia, Proteomic analysis |
Contact List
| Xiang Cao | |
|---|---|
| contact affiliation | Nanjing Drum Tower Hospital |
| contact email | caoxiang@njglyy.com |
| lab head | |
| Siyi Xu | |
| contact affiliation | Nanjing Drum Tower Hospital |
| contact email | xusiyi07@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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