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PXD068932

PXD068932 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The H3K27me3 reader UAD-2 recruits a TAF-12-containing transcription machinery to initiate piRNA expression within heterochromatic clusters
Description	In this project, we performed immunoprecipitation (IP) experiments from whole-worm lysates of uad-2::gfp::3xflag animals and identified putative UAD-2-interacting partners through quantitative mass spectrometry (MS). Using FLAG-tagged TAF-12 as bait, we conversely substantiated the interaction between UAD-2 and TAF-12 via the IP-MS method.
HostingRepository	iProX
AnnounceDate	2025-09-28
AnnouncementXML	Submission_2025-09-29_00:12:46.657.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xinya Huang
SpeciesList	scientific name: Caenorhabditis elegans; NCBI TaxID: 6239;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-09-29 00:12:18	ID requested
⏵ 1	2025-09-29 00:12:47	announced

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: UAD-2, TAF-12, piRNA transcription

Contact List

Shouhong Guang
contact affiliation	University of Science and Technology of China
contact email	sguang@ustc.edu.cn
lab head
Xinya Huang
contact affiliation	University of Science and Technology of China
contact email	hr1996@mail.ustc.edu.cn
dataset submitter

Full Dataset Link List

iProX dataset URI