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PXD068914

PXD068914 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe Roles of PFOA and PFOS on Human Sperm Capacitation
DescriptionPFOS and PFOA are persistent organic pollutants known to impair human reproduction, but their effects and molecular mechanisms on human sperm remain unclear. Here, we conducted comprehensive proteomic and phosphoproteomic profiling of human sperm exposed to PFOS and PFOA during capacitation to provide systematic insights.
HostingRepositoryiProX
AnnounceDate2025-09-28
AnnouncementXMLSubmission_2026-02-12_22:53:11.094.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPeibei Sun
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListphosphorylated residue
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-09-28 17:58:55ID requested
12026-02-12 22:53:12announced
Publication List
Gao L, Pan N, Xu W, Li G, Li K, Shi J, Sun P, PFOA and PFOS impair human sperm capacitation by inducing mitochondrial-mediated apoptosis and ferroptosis. Ecotoxicol Environ Saf, 309():119743(2026) [pubmed]
Keyword List
submitter keyword: PFOA, PFOS, Human sperm, Capacitation
Contact List
Peibei Sun
contact affiliationHangzhou Medical College
contact emailpeibeisun@hmc.edu.cn
lab head
Peibei Sun
contact affiliationHangzhou Medical College
contact emailpeibeisun@hmc.eu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI