PXD068894

PXD068894 is an original dataset announced via ProteomeXchange.

Title	Neuropeptidomics of the cockroach Rhyparobia maderae to characterize the neuropeptide landscape of the cockroach's circadian clock
Description	The circadian clock of Rhyparobia maderae is the accessory medulla (AME) in the optic lobes of the brain. Controlled by compound ocular photoreceptors, the cockroach clock orchestrates circadian rhythms in physiology and behavior synchronized with environmental light-dark cycles. Approximately 240 neurons, rich in partially co-localized neuropeptides innervate the AME. Since the identity and function of most of these neuropeptides are unknown in the cockroach, we identify the neuropeptidome, a combination of analyses of brain/retrocerebral complex and AME extracts by Q-Exactive Orbitrap mass spectrometry (MS).
HostingRepository	PRIDE
AnnounceDate	2025-11-17
AnnouncementXML	Submission_2025-11-16_16:30:33.575.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD068894
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Susanne Neupert
SpeciesList	scientific name: Rhyparobia maderae; NCBI TaxID: NEWT:36963;
ModificationList	monomethylated residue; sulfated residue; 2-pyrrolidone-5-carboxylic acid (Glu); half cystine; 2-pyrrolidone-5-carboxylic acid (Gln); phosphorylated residue; C1-amidated residue; acetylated residue; monohydroxylated residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2025-09-27 05:35:06	ID requested
⏵ 1	2025-11-16 16:30:34	announced

10.6019/PXD068894;

Neupert S, Shoaib SH, Schendzielorz J, Zolmon H, Hering L, Stengl M, to Characterize the Neuropeptide Landscape of the Cockroach's Circadian Clock. J Proteome Res, 24(11):5370-5389(2025) [pubmed]

10.1021/acs.jproteome.4c01069;

submitter keyword: LC-MS mass spectrometry, insect,neuropeptidomics, circadian clock

Susanne Neupert
contact affiliation	University of Kassel - Department of Animal Physiology
contact email	sneupert@uni-kassel.de
lab head
Susanne Neupert
contact affiliation	University Kassel
contact email	sneupert@uni-kassel.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD068894

PRIDE project URI

• PRIDE
  1. PXD068894
     1. Label: PRIDE project
     2. Name: Neuropeptidomics of the cockroach Rhyparobia maderae to characterize the neuropeptide landscape of the cockroach's circadian clock