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PXD068153

PXD068153 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleResearch on PFM01 in the field of antibacterial and its bactericidal mechanism.
DescriptionInvestigating PFM01's bactericidal mechanism reveals its impact on the permeability and fluidity of S. aureus cell membranes, suggesting targeted effects on specific membrane components. The checkerboard method and subsequent proteomic and whole-genome sequencing analyses under PFM01 pressure elucidate alterations in membrane phospholipids, up-regulation of transmembrane and membrane-associated proteins, and identification of mutations in resistant strains, providing insights into PFM01's antibacterial action.
HostingRepositoryiProX
AnnounceDate2025-09-05
AnnouncementXMLSubmission_2026-08-31_00:57:00.758.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterCongkong Li
SpeciesList scientific name: Staphylococcus aureus subsp. aureus NCTC 8325; NCBI TaxID: 93061;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-09-07 23:44:14ID requested
12026-08-31 00:57:01announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: PFM01
Contact List
Zhijian Yu
contact affiliationNanshan People's Hospital
contact emailyuzhijiansmu@163.com
lab head
Congkong Li
contact affiliationNanshan People's Hospital
contact email512445441@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI