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PXD068153
PXD068153 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Research on PFM01 in the field of antibacterial and its bactericidal mechanism. |
| Description | Investigating PFM01's bactericidal mechanism reveals its impact on the permeability and fluidity of S. aureus cell membranes, suggesting targeted effects on specific membrane components. The checkerboard method and subsequent proteomic and whole-genome sequencing analyses under PFM01 pressure elucidate alterations in membrane phospholipids, up-regulation of transmembrane and membrane-associated proteins, and identification of mutations in resistant strains, providing insights into PFM01's antibacterial action. |
| HostingRepository | iProX |
| AnnounceDate | 2025-09-05 |
| AnnouncementXML | Submission_2026-08-31_00:57:00.758.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Congkong Li |
| SpeciesList | scientific name: Staphylococcus aureus subsp. aureus NCTC 8325; NCBI TaxID: 93061; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-09-07 23:44:14 | ID requested | |
| ⏵ 1 | 2026-08-31 00:57:01 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: PFM01 |
Contact List
| Zhijian Yu | |
|---|---|
| contact affiliation | Nanshan People's Hospital |
| contact email | yuzhijiansmu@163.com |
| lab head | |
| Congkong Li | |
| contact affiliation | Nanshan People's Hospital |
| contact email | 512445441@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |




