⮝ Full datasets listing
PXD067964
PXD067964 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Stable Coordination Unlocks Ligand-accelerated Transition Metal Catalysis on Proteins |
| Description | This project investigates in situ deprotection reactions catalyzed by the Ni–BCS system in MC38 cells and the subsequent impact on the immunopeptidome. Two independent MC38 cell preparations (2 × 10⁷ cells each) were pulsed with either the P2 peptide or P2 peptide followed by Ni–BCS catalyzed in situ deprotection (P2+Ni). MHC-associated peptides were analysed by Immunoprecipitation-Mass Spectrometry. |
| HostingRepository | iProX |
| AnnounceDate | 2025-09-02 |
| AnnouncementXML | Submission_2026-03-04_22:46:25.059.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Siyang Liu |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-09-02 00:01:30 | ID requested | |
| ⏵ 1 | 2026-03-04 22:46:26 | announced |
Publication List
| Wang Z, Xiang F, Liao X, Wu Q, Jiao J, Bi A, Liu S, Wang D, Wang M, Guo Z, Li JP, Inert Complexes Unlock Ligand-Accelerated Transition-Metal Catalysis on Proteins. Angew Chem Int Ed Engl, 65(10):e22057(2026) [pubmed] |
Keyword List
| submitter keyword: Ni–BCS catalysis, in situ deprotection, immunopeptidome |
Contact List
| Jie Li | |
|---|---|
| contact affiliation | Nanjing University |
| contact email | jieli@nju.edu.cn |
| lab head | |
| Siyang Liu | |
| contact affiliation | Nanjing University |
| contact email | 161230016@smail.nju.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
