PXD067823

PXD067823 is an original dataset announced via ProteomeXchange.

Title	Covalent labelling of UNC119 with alkyl bromide compound 7
Description	UNC119 protein was treated with compound 7 (10:1 in excess, overnight) to see if covalent modification can be achieved with this alkyl bromide derivative at E163. Untreated UNC119 was used as negative control in comparison.
HostingRepository	PRIDE
AnnounceDate	2026-01-08
AnnouncementXML	Submission_2026-01-08_00:58:03.573.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Farnusch Kaschani
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	carbamoylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-28 03:23:31	ID requested
⏵ 1	2026-01-08 00:58:04	announced

Dataset with its publication pending

submitter keyword: Targeted covalent inhibitors,UNC119, Glu-targeted inhibition, alkyl bromide reactivity

Farnusch Kaschani
contact affiliation	Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany
contact email	farnusch.kaschani@uni-due.de
lab head
Farnusch Kaschani
contact affiliation	University Duisburg-Essen
contact email	farnusch.kaschani@uni-due.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD067823

PRIDE project URI

• PRIDE
  1. PXD067823
     1. Label: PRIDE project
     2. Name: Covalent labelling of UNC119 with alkyl bromide compound 7