PXD067794

PXD067794 is an original dataset announced via ProteomeXchange.

Title	Microbiome adaptation of rewilded cattle
Description	Rewilding of animals holds promise for restoring industrialized microbiomes back to their ancestral state, enhancing resilience and reducing the requirement for therapeutic interventions. Using a “two-eyed seeing” approach we studied the Muus Muus, a herd of rewilded cattle in the traditional territory of the Tla-o-qui-aht Peoples on Meares Island. These cattle have a browser-grazer lifestyle, foraging on old growth forest plants, native grasses, and seaweeds, reminiscent of their extinct ancestor, the auroch. Using high-resolution, multi-layered omics and trnL-P6 sequencing we confirmed digestion of unconventional forages, including salal, cedar, and green seaweed. The resistome of the rewilded cattle displayed significantly less abundant AMR genes, offering a glimpse into the profiles of non-selected ruminant microbiomes and presenting new opportunities to mitigate the prevailing AMR crisis.
HostingRepository	PRIDE
AnnounceDate	2026-02-25
AnnouncementXML	Submission_2026-02-25_07:26:13.181.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thea Andersen
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: NEWT:9913;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-27 05:14:40	ID requested
⏵ 1	2026-02-25 07:26:13	announced

Dataset with its publication pending

submitter keyword: None

Phillip Pope
contact affiliation	Centre for Microbiome Research, School of Biomedical Sciences, Queensland University of Technology (QUT), Translational Research Institute, Woolloongabba, QLD, Australia
contact email	phil.pope@qut.edu.au
lab head
Thea Andersen
contact affiliation	Norwegian University of Life Sciences
contact email	thea.os.andersen@nmbu.no
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD067794

PRIDE project URI

• PRIDE
  1. PXD067794
     1. Label: PRIDE project
     2. Name: Microbiome adaptation of rewilded cattle