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PXD067774

PXD067774 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification and Characterization of Extracellular Vesicles Released from CSFV-Infected PK-15 Cells
Description	Extracellular vesicles (EVs) are membrane-bound particles released by cells, capable of carrying diverse cytoplasmic constituents and influencing the physiological functions of both proximal and distant recipient cells. Because EVs can protect their cargo from immune surveillance, they are exploited by viruses to evade neutralizing antibodies. Classical swine fever virus (CSFV) is hypothesized to utilize EVs for dissemination among susceptible cells. Analyzing the composition of these virus-associated EVs can reveal critical steps in the viral life cycle. Therefore, we isolated EVs mediating CSFV transmission via differential centrifugation and size-exclusion chromatography, and characterized their molecular composition. This work establishes a foundation for investigating key mechanisms in the CSFV life cycle.
HostingRepository	iProX
AnnounceDate	2025-08-27
AnnouncementXML	Submission_2025-08-26_20:21:59.770.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Liangcai Da
SpeciesList	scientific name: Classical swine fever virus; NCBI TaxID: 11096;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-26 20:21:40	ID requested
⏵ 1	2025-08-26 20:22:00	announced

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: CSFV EVs

Contact List

Zengjun Lu
contact affiliation	Lanzhou University
contact email	luzj@lzu.edu.cn
lab head
Liangcai Da
contact affiliation	Lanzhou University
contact email	dalc2024@lzu.edu.cn
dataset submitter

Full Dataset Link List

iProX dataset URI