PXD067559

PXD067559 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	The rapid manufacture of biologics using mRNA
Description	We evaluate bevacizumab, a monoclonal antibody, expression in time course from mRNA transient transfection in CHO cells using MS. We transiently transfected bevacizumab heavy and light chain mRNAs into CHO-S WT using lipoplex. Later, we analysed the bevacizumab protein intracellularly.
HostingRepository	PRIDE
AnnounceDate	2025-12-22
AnnouncementXML	Submission_2025-12-21_17:40:36.577.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thornwit Chavalparit
SpeciesList	scientific name: Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus); NCBI TaxID: NEWT:10029;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-21 05:39:24	ID requested
⏵ 1	2025-12-21 17:40:37	announced

Publication List

Chavalparit T, Barry C, Gunter H, Gillard M, Mercer T, Marcellin E, Rapid expression of therapeutic antibodies in mammalian cells via mRNA transfection. MAbs, 18(1):2599584(2026) [pubmed]
10.1080/19420862.2025.2599584;

Chavalparit T, Barry C, Gunter H, Gillard M, Mercer T, Marcellin E, Rapid expression of therapeutic antibodies in mammalian cells via mRNA transfection. MAbs, 18(1):2599584(2026) [pubmed]

10.1080/19420862.2025.2599584;

Keyword List

submitter keyword: CHO, MS, Protein expression, Monoclonal antibody,mRNA transien transfection

submitter keyword: CHO, MS, Protein expression, Monoclonal antibody,mRNA transien transfection

Contact List

Esteban Marcellin
contact affiliation	Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland
contact email	e.marcellin@uq.edu.au
lab head
Thornwit Chavalparit
contact affiliation	Australian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland
contact email	t.chavalparit@uq.edu.au
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD067559
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD067559

PRIDE project URI

Repository Record List

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