PXD067554

PXD067554 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Multiomics Study of Corylin in Modulating Longevity and Healthspan
Description	To elucidate the molecular mechanisms underlying Corylin-mediated delay of aging, we employed an integrated multi-omics approach—comprising proteome, phosphoproteome, and lysine acetylome analyses—using tissue samples from quadriceps, kidney, and liver collected from both male and female C57BL/6J mice. Comparative profiling across three groups—young, aged, and aged mice treated with Corylin—enabled a systematic characterization of Corylin-induced molecular alterations associated with aging.
HostingRepository	PRIDE
AnnounceDate	2025-08-21
AnnouncementXML	Submission_2025-08-21_06:37:57.099.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD067554
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Yu-Tsun Lin
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; methylthiolated residue; phosphorylated residue; acetylated residue; monohydroxylated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-21 05:25:02	ID requested
⏵ 1	2025-08-21 06:37:57	announced

Publication List

10.6019/PXD067554;

10.6019/PXD067554;

Keyword List

submitter keyword: Mouse aging model, Tandem Mass Tag (TMT), Phosphoproteomimcs,Corylin, Longevity, Proteomics, Lysine acetylome

submitter keyword: Mouse aging model, Tandem Mass Tag (TMT), Phosphoproteomimcs,Corylin, Longevity, Proteomics, Lysine acetylome

Contact List

Chin-Chuan Chen
contact affiliation	Graduate Institute of Natural Products, Chang Gung University, Taoyuan, Taiwan
contact email	chinchuan@mail.cgu.edu.tw
lab head
Yu-Tsun Lin
contact affiliation	Chang Gung University
contact email	doreenlin1230@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD067554
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD067554

PRIDE project URI

Repository Record List

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