PXD067446 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic and phosphoproteomic study in the retina, choroid, and sclera of guinea pigs with form-deprivation myopia |
| Description | Myopia is a growing global public health concern. Recent studies have revealed that the regulation of eye growth occurs via a complex signaling cascade, which originates in the retina and across the choroid to the sclera. Identifying key proteins and specific biological processes in the retina, choroid, and sclera is crucial for understanding the molecular mechanisms underlying myopia development. This study provides an in-depth proteomic and phosphoproteomic atlas of the retina, choroid, and sclera in guinea pigs with form-deprivation myopia, uncovering the potential molecular mechanisms driving the progression of myopia. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-17 |
| AnnouncementXML | Submission_2025-11-16_16:42:50.817.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yifan Song |
| SpeciesList | scientific name: Cavia porcellus (Guinea pig); NCBI TaxID: NEWT:10141; |
| ModificationList | phosphorylated residue |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-08-18 00:51:14 | ID requested | |
| ⏵ 1 | 2025-11-16 16:42:51 | announced | |
Publication List
| 10.1016/j.mcpro.2025.101069; |
| Song Y, Xu Z, Li HT, Xie Y, Zhao L, Feng J, Luo A, Dai J, Li J, Guo X, Song J, Bi H, Proteomic and Phosphoproteomic Characteristics of the Retina, Choroid, and Sclera in Guinea Pigs with Form-Deprivation Myopia. Mol Cell Proteomics, 24(11):101069(2025) [pubmed] |
Keyword List
| submitter keyword: Retina, Choroid, Form-deprivation myopia, Sclera,Proteomics and phosphoproteomics |
Contact List
| Hongsheng Bi |
|---|
| contact affiliation | Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine |
| contact email | hongshengbi1@163.com |
| lab head | |
| Yifan Song |
|---|
| contact affiliation | Shandong University of Traditional Chinese Medicine |
| contact email | songyifan0505@163.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD067446 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD067446
- Label: PRIDE project
- Name: Proteomic and phosphoproteomic study in the retina, choroid, and sclera of guinea pigs with form-deprivation myopia
