PXD067421

PXD067421 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	VCPIP1 Drives Diabetic Cardiomyopathy by Deubiquitinating AMPKγ1 and Preventing AMPKα-γ Subunit Assembly in Cardiomyocytes
Description	Protein ubiquitination modifications contribute to cardiomyocyte homeostasis and pathophysiology in diabetic cardiomyopathy (DCM). Yet the roles of deubiquitinating enzymes (DUBs) in DCM remain poorly defined. Here, we aimed to clarify the regulatory function of a DUB, valosin-containing protein interacting protein 1 (VCPIP1), in DCM and uncover the molecular mechanisms.
HostingRepository	PRIDE
AnnounceDate	2026-03-16
AnnouncementXML	Submission_2026-03-16_08:33:33.882.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	liu guoxuan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-16 20:33:18	ID requested
⏵ 1	2026-03-16 08:33:34	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Flag VCPIP1，Flag empty vector plasmid

submitter keyword: Flag VCPIP1，Flag empty vector plasmid

Contact List

XUE HAN
contact affiliation	Zhejiang Provincial Key Laboratory of Laboratory Animals and Safety Research
contact email	13819113623@163.com
lab head
liu guoxuan
contact affiliation	Hangzhou Medical College
contact email	872789615@qq.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD067421
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD067421

PRIDE project URI

Repository Record List

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