PXD067418

PXD067418 is an original dataset announced via ProteomeXchange.

Title	Metarhizium anisopliae exposed to an infection system triggering medium
Description	This dataset is associated with a study on the horizontal transfer of transposable elements (TEs) mediated by "Starships", large mobile genetic elements found in fungi of the subphylum Pezizomycotina. Comparative genome analysis of two strains of the entomopathogenic fungus Metarhizium anisopliae revealed the introduction and subsequent expansion of 43 TEs in one strain, totaling 508 perfect copies, following the arrival of a Starship carrying 73 TEs. This expansion led to extensive structural genome rearrangements, including the formation of a new chromosome and a loss of pathogenicity, likely linked to the relocalization and reduced expression of virulence-related genes, such as the subtilisin-like protease PR1C. Analysis of 618 published Starships showed that most carry TEs, with many exhibiting evidence of horizontal transfer and subsequent expansion. These findings highlight Starships as key vectors for TE horizontal transfer in fungi. The proteomic data submitted here aim to complement the investigation of functional changes associated with the observed genome reorganization.
HostingRepository	PRIDE
AnnounceDate	2026-01-12
AnnouncementXML	Submission_2026-01-12_08:41:35.298.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD067418
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Lucelia Santi
SpeciesList	scientific name: Metarhizium anisopliae; NCBI TaxID: NEWT:5530;
ModificationList	carbamoylated residue; monohydroxylated residue; iodoacetic acid derivatized residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-16 14:53:46	ID requested
⏵ 1	2026-01-12 08:41:35	announced

10.6019/PXD067418;

submitter keyword: Metarhizium anisopliae

Proteomic

Lucélia Santi
contact affiliation	Faculdade de Farmácia; Centro de Biotecnologia, Federal University of Rio Grande do Sul (UFRGS), Porto Alegre/RS, Brazil
contact email	lucelia.santi@ufrgs.br
lab head
Lucelia Santi
contact affiliation	Universidade Federal do Rio Grande do Sul
contact email	lucelia.santi@ufrgs.br
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD067418

PRIDE project URI

• PRIDE
  1. PXD067418
     1. Label: PRIDE project
     2. Name: Metarhizium anisopliae exposed to an infection system triggering medium