PXD067345 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Mapping the DPP9 Interactome by Proximity Labeling |
| Description | Dipeptidyl peptidase 9 (DPP9) is an amino peptidase with the unusual ability to cleave a peptide bond post-proline. Its function affects immunity, DNA-repair, cell signaling, memory and neonatal survival; its dysregulation is linked to cancer and immune-related disorders. While most studies focus on its canonical catalytic function, scaffolding functions of DPP9 are just beginning to emerge. To define the interactome of DPP9, we used TurboID-based proximity labeling in DPP9 HEK293 knock-out cells reconstituted with doxycycline-inducible miniTurboID–DPP9. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-31 |
| AnnouncementXML | Submission_2026-08-30_16:13:44.114.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Oded Kleifeld |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Exploris 480; Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-08-14 02:46:36 | ID requested | |
| ⏵ 1 | 2026-08-30 16:13:44 | announced | |
Publication List
| Wirtgen VE, Saied L, Zolg S, Alonso MC, Mayer B, Donzelli L, Maurer U, Timmers HTM, Knobeloch KP, Kleifeld O, Geiss-Friedlander R, Proximity labeling reveals non-catalytic interactions between DPP9 and ubiquitin signaling complexes. Cell Mol Life Sci, 83(1):93(2026) [pubmed] |
| 10.1007/s00018-025-06021-z; |
Keyword List
| submitter keyword: Proximity labeling,DPP9, TurboID |
Contact List
| Oded Kleifeld |
|---|
| contact affiliation | Faculty of Biology Technion- Israel Institute of Technology Technion City, Haifa, Israel |
| contact email | okleifeld@technion.ac.il |
| lab head | |
| Oded Kleifeld |
|---|
| contact affiliation | Technion |
| contact email | okleifeld@technion.ac.il |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD067345 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD067345
- Label: PRIDE project
- Name: Mapping the DPP9 Interactome by Proximity Labeling
