PXD067327 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteome and phosphoproteome profiling of HCT116 colon cancer cells with PP2A subunit PR130 deletion and herpes simplex virus HSV-1 infection |
| Description | Label-free quantitative proteomics and phosphoproteomics experiments were performed to study the impact of PP2A subunit PR130 deletion and herpes simplex virus HSV-1 infection on differential protein expression and phosphorylation changes in HCT116 human colon cancer cells. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-05-16 |
| AnnouncementXML | Submission_2026-05-16_10:30:59.706.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jia-Xuan Chen |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; scientific name: Human alphaherpesvirus 1; NCBI TaxID: NEWT:10298; |
| ModificationList | phosphorylated residue |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-08-13 19:01:55 | ID requested | |
| ⏵ 1 | 2026-05-16 10:31:00 | announced | |
Publication List
| 10.1002/advs.202523697; |
| Jungwirth J, Jacob CF, Nguyen A, Beyer M, Mieland AO, Dejung M, Chen JX, Brenner W, Ehrhardt C, Henke A, Kr, ä, mer OH, The Host Cell Factor Phosphatase-2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type-1. Adv Sci (Weinh), ():e23697(2026) [pubmed] |
Keyword List
| submitter keyword: PR130, HSV-1,PP2A, phosphoproteomics |
Contact List
| Oliver H. Krämer |
|---|
| contact affiliation | Universitätsmedizin Mainz, Germany |
| contact email | okraemer@uni-mainz.de |
| lab head | |
| Jia-Xuan Chen |
|---|
| contact affiliation | Institute of Molecular Biology |
| contact email | j.chen@imb-mainz.de |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/05/PXD067327 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD067327
- Label: PRIDE project
- Name: Proteome and phosphoproteome profiling of HCT116 colon cancer cells with PP2A subunit PR130 deletion and herpes simplex virus HSV-1 infection
