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PXD067298

PXD067298 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDeep Quantitative Proteomic Profiling of Microglia from the EAE Mouse Model
DescriptionMicroglia, the resident immune cells of the central nervous system (CNS), are critically involved in the pathogenesis of multiple sclerosis (MS). To better understand the molecular changes in these cells during neuroinflammation, we performed high-depth quantitative proteomics on microglia isolated from a murine model of MS, experimental autoimmune encephalomyelitis (EAE). This dataset provides a comprehensive proteomic landscape of EAE microglia, offering valuable insights into the cellular mechanisms driving MS pathology.
HostingRepositoryPRIDE
AnnounceDate2026-06-15
AnnouncementXMLSubmission_2026-06-15_06:02:08.096.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJiahong Li
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF HT
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-08-13 06:53:52ID requested
12026-06-15 06:02:08announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: EAE, Neuroinflammation, CNS, Mouse, Proteomics,Microglia
Contact List
Jiahong Li
contact affiliationXuanwu Hospital Capital Medical University Department of Neurology
contact emaillijiahonggabnie@163.com
lab head
Jiahong Li
contact affiliationXuanwu Hospital Capital Medical University Department of Neurology
contact emaillijiahonggabnie@163.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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