PXD067270

PXD067270 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic profiling during normothermic perfusion predicts liver graft quality and outcomes after transplantation
Description	This study investigates the proteomic dynamics of human liver grafts during normothermic machine perfusion (NMP), using mass spectrometry-based analysis. A total of 16 donor livers were perfused with NMP and sampled at three distinct time points to assess molecular changes and their association with post-transplant outcomes. The aim was to identify proteomic biomarkers predictive of graft quality and biliary complications.
HostingRepository	PRIDE
AnnounceDate	2026-04-27
AnnouncementXML	Submission_2026-04-26_19:11:02.514.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dupuy Jean-William
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-12 11:06:16	ID requested
⏵ 1	2026-04-26 19:11:03	announced

Publication List

Jeddou H, Raymond AA, Dupuy JW, Dourthe C, Prudhomme H, Nejma EB, Tzedakis S, Turlin B, Allaume P, Boudjema K, Samson M, Proteomic Trajectories of Metabolic and Proteostatic Adaptation During Normothermic Liver Perfusion. Liver Int, 46(5):e70629(2026) [pubmed]
10.1111/liv.70629;

Jeddou H, Raymond AA, Dupuy JW, Dourthe C, Prudhomme H, Nejma EB, Tzedakis S, Turlin B, Allaume P, Boudjema K, Samson M, Proteomic Trajectories of Metabolic and Proteostatic Adaptation During Normothermic Liver Perfusion. Liver Int, 46(5):e70629(2026) [pubmed]

10.1111/liv.70629;

Keyword List

submitter keyword: Quantitative proteomics, Graft viability, Normothermic machine perfusion, biliary complications,Liver transplantation

submitter keyword: Quantitative proteomics, Graft viability, Normothermic machine perfusion, biliary complications,Liver transplantation

Contact List

Heithem Jeddou
contact affiliation	Institut de recherche en santé, environnement et travail (IRSET). 9 Av. du Professeur Léon Bernard, 35000 Rennes
contact email	heithem.jeddou@chu-rennes.fr
lab head
Dupuy Jean-William
contact affiliation	OncoProt plateform, UAR TBMCore CNRS 3427 INSERM US005 University of Bordeaux
contact email	jean-william.dupuy@u-bordeaux.fr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD067270
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD067270

PRIDE project URI

Repository Record List

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