PXD067169

PXD067169 is an original dataset announced via ProteomeXchange.

Title	Glycyrrhiza polysaccharide alleviates LPS-induced immune stress in broilers: integrated transcriptomic and proteomic analysis
Description	This study aimed to investigate the alleviating effects and potential mechanisms of Glycyrrhiza polysaccharide (GP) on lipopolysaccharide (LPS)-induced immune stress in broiler chickens. A total of 240 one-day-old AA broiler chicks were randomly assigned to a 2×2 factorial design, comprising a control group and a GP group (diet supplemented with 1500 mg/kg GP). From day 10, birds were injected with either LPS or physiological saline to establish an immune stress model. The experiment was divided into three phases: the initial phase (days 1–10), the stress phase (days 10–28), and the recovery phase (days 28–35). The effects of GP intervention were systematically evaluated in terms of growth performance, immune organ indices, serum inflammatory cytokines, intestinal morphology, and goblet cell count. Furthermore, the underlying molecular mechanisms were explored through integrated transcriptomic and proteomic analyses of spleen tissue.
HostingRepository	iProX
AnnounceDate	2025-08-09
AnnouncementXML	Submission_2026-02-08_17:51:48.319.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Shuyan Wu
SpeciesList	scientific name: Gallus gallus; NCBI TaxID: 9031;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-08-10 20:59:53	ID requested
⏵ 1	2026-02-08 17:51:48	announced

Dataset with its publication pending

submitter keyword: Glycyrrhiza polysaccharide, broiler chickens, Immune Stress

Tiyu Li
contact affiliation	Inner Mongolia Minzu University
contact email	litiyu2050@163.com
lab head
Shuyan Wu
contact affiliation	Inner Mongolia Minzu University
contact email	1271315613@qq.com
dataset submitter

iProX dataset URI