PXD066985
PXD066985 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Curcuminoids Suppress EV-D68 Infection via the CRYAB-RBM26 Axis by Reversing Viral Hijacking of Nucleic Acid Metabolism and Activating IFN Pathways |
| Description | This study demonstrates that curcuminoids exert antiviral effects by upregulating CRYAB, which in turn stabilizes RBM26-mediated nucleic acid metabolism pathways. Additionally, CRYAB contributes to the maintenance of the interferon protein pool, leading to the activation of IFN-dependent antiviral pathways. |
| HostingRepository | iProX |
| AnnounceDate | 2025-08-06 |
| AnnouncementXML | Submission_2025-08-06_00:32:53.055.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Lu Wang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | ubiquitination signature dipeptidyl lysine; phosphorylated residue |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-08-06 00:32:35 | ID requested | |
| ⏵ 1 | 2025-08-06 00:32:53 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: viral infection, EV-D68, Curcuminoids, CRYAB, RBM26, nucleotide metabolism |
Contact List
| Tingting Chen | |
|---|---|
| contact affiliation | Chongqing Medical University |
| contact email | cherrychen@cqmu.edu.cn |
| lab head | |
| Lu Wang | |
| contact affiliation | Chongqing Medical University |
| contact email | 974978782@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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