⮝ Full datasets listing
PXD066898
PXD066898 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Biomaterial silk hydrogel to deliver nanovesicles |
| Description | Extracellular vesicle (EV) therapeutics are an emerging frontier for tissue repair and regeneration with clinical utility, yet challenges in their manufacturer scalability, mode of administration for sustained bioactivity, and tissue-specific retention limit their translation. This study addresses these hurdles through an innovative biomaterial platform combining highly scalable iPSC-derived NVs with adhesive silk hydrogel patches for localized, sustained administration - offering a functional biodelivery platform. The versatility of this platform for localized, extended delivery of NVs that retain their integrity and bioactivity in cardiac cell remodeling can result in significant advancements across the fields of nanomedicine and biomedical engineering. |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-06-14 |
| AnnouncementXML | Submission_2026-06-14_19:12:13.481.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | David Greening |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | Acetyl |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-08-03 22:01:58 | ID requested | |
| ⏵ 1 | 2026-06-14 19:12:14 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: silk, Biomaterial, nanovesicles, extracellular vesicles, DatasetType:Proteomics |
Contact List
| David Greening | |
|---|---|
| contact affiliation | Baker Heart & Diabetes Institute |
| contact email | david.greening@baker.edu.au |
| lab head | |
| David Greening | |
| contact affiliation | Baker Heart & Diabetes Institute |
| contact email | david.greening@baker.edu.au |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v10/MSV000098711/ |
