PXD066348

PXD066348 is an original dataset announced via ProteomeXchange.

Title	O-GlcNAc Glycosylation 4D-Label free Quantitative Proteomics Bioinformatics Analysis Report
Description	O-linked β-N-acetylglucosamine (O-GlcNAc) modification is a dynamic post-translational modification that involves the reversible attachment of N-acetylglucosamine to serine or threonine residues of nuclear, cytoplasmic, and mitochondrial proteins. This modification is critical for regulating cellular processes such as signal transduction, transcription, translation, protein degradation, and cellular localization. Aberrant O-GlcNAcylation has been implicated in numerous pathological conditions, including diabetes, cardiovascular diseases, neurodegenerative disorders, and cancers, highlighting the need for precise methods to study its dynamics across biological systems.
HostingRepository	iProX
AnnounceDate	2025-11-26
AnnouncementXML	Submission_2026-08-25_20:18:12.994.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wenhu Fan
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2025-07-21 00:52:36	ID requested
⏵ 1	2026-08-25 20:18:13	announced

Li X, Xu H, Chang Y, Zhang Y, Xu H, Yin X, Zhang W, Luo Y, Lu W, Fan W, Ruan W, Shen J, Li Z, Du S, Bentum-Ennin L, Ni J, Gao W, Li J, Hu W, Yang W, Gao Y, Gu H, Circulating NSUN6 serves as a prognostic biomarker for early metastasis in HCC via hippo pathway modulation. J Exp Clin Cancer Res, ():(2026) [pubmed]

submitter keyword: O-GlcNAc

Hao Gu
contact affiliation	Anhui Medical University
contact email	guhao@ahmu.edu.cn
lab head
Wenhu Fan
contact affiliation	Anhui Medical University
contact email	2445010051@stu.ahmu.edu.cn
dataset submitter

iProX dataset URI