PXD066231 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Serum Proteomic Profiling Reveals Immune and Inflammatory Mechanisms Driving Susceptibility to Buffalo Fly-Induced Skin Lesions in Cattle |
| Description | Buffalo fly (Haematobia irritans exigua) infestation in cattle poses a significant challenge to animal health and welfare, causing blood loss and often painful skin lesions. These lesions can reduce the value of cattle in saleyards, make cattle unacceptable for certain markets, and provide a focus for secondary infections; yet, the underlying mechanisms of susceptibility remain poorly understood. This study employed SWATH-MS-based quantitative proteomics to investigate systemic proteomic profiles in lesion-susceptible (HL) and lesion-resistant (NL) cattle across multiple time points, aiming to identify key proteins and pathways associated with lesion development and resilience. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-12 |
| AnnouncementXML | Submission_2026-01-11_16:33:31.851.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ali Raza |
| SpeciesList | scientific name: Bos taurus (Bovine); NCBI TaxID: NEWT:9913; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | ZenoTOF 7600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-07-16 17:38:02 | ID requested | |
| ⏵ 1 | 2026-01-11 16:33:32 | announced | |
Publication List
| Raza A, Naseem MN, Kamran M, Nouwens A, Juli MSB, Constantinoiu C, Tabor A, Schulz B, James P, Serum proteomic profiling reveals immune and inflammatory mechanisms driving susceptibility to buffalo fly-induced skin lesions in cattle. Sci Rep, 16(1):769(2025) [pubmed] |
| 10.1038/s41598-025-30396-5; |
Keyword List
| submitter keyword: Acute phase response, Susceptibility,Buffalo fly (Haematobia irritans exigua), Immune Dysregulation, Cattle, Quantitative Proteomics, Biomarkers, Skin lesions |
Contact List
| Ali Raza |
|---|
| contact affiliation | University of Queensland |
| contact email | a.raza@uq.edu.au |
| lab head | |
| Ali Raza |
|---|
| contact affiliation | University of Queensland |
| contact email | a.raza@uq.edu.au |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD066231 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD066231
- Label: PRIDE project
- Name: Serum Proteomic Profiling Reveals Immune and Inflammatory Mechanisms Driving Susceptibility to Buffalo Fly-Induced Skin Lesions in Cattle
