⮝ Full datasets listing
PXD066149
PXD066149 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Identification of Tim-4 Binding Proteins in Peritoneal Macrophages |
| Description | T-cell immunoglobulin and mucin domain containing 4 (Tim-4) is known to suppress macrophage inflammatory responses in various diseases, but its role and underlying mechanism in peritoneal macrophage (PEMs) with LPS stimulation are unknown. PEMs were isolated from Tim-4fl/fl mice and LysM-Cre; Tim-4fl/fl mice, followed by stimulation with 100 ng/mL LPS for 24 hours. After validating the successful knockout of Tim-4 in macrophages, mass spectrometry was employed to identify differentially expressed proteins in PEMs. |
| HostingRepository | iProX |
| AnnounceDate | 2025-07-14 |
| AnnouncementXML | Submission_2026-01-04_00:34:25.263.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xiao Wang |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-07-15 01:11:18 | ID requested | |
| ⏵ 1 | 2026-01-04 00:34:25 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Tim-4，Peritoneal Macrophages |
Contact List
| Wen Liu | |
|---|---|
| contact affiliation | Shandong First Medical University & Shandong Academy of Medical Sciences |
| contact email | liuwen@sdfmu.edu.cn |
| lab head | |
| Xiao Wang | |
| contact affiliation | Shandong First Medical University & Shandong Academy of Medical Sciences |
| contact email | 1257027970@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
